Human Polyomavirus 7 (HPyV7)

307.212,550.07

Validated qPCR / RT-PCR kit for Human Polyomavirus 7 (HPyV7)

Detection channel: FAM (518nm)

Available in different versions:

-Direct One-Step PCR (extraction-less direct detection)

-One-Step PCR (extraction kit needed)

-Standard PCR (extraction kit and RT step needed)

-Oligo (without PCR mix)

In 100/200/500 reactions, with optional copy number positive control

(Not for use in diagnostic procedures)

Clear
SKU: PCR-00364-K Categories: , , ,

Description

Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. 13 species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent. Most of these viruses are very common and typically asymptomatic in most human populations studied.

All the polyomaviruses are highly common childhood and young adult infections. Most of these infections appear to cause little or no symptoms. These viruses are probably lifelong persistent among almost all adults. Diseases caused by human polyomavirus infections are most common among immunocompromised people.

HPyV7 has been associated in case reports with a skin condition in immunocompromised patients—HPyV7-related epithelial hyperplasia[10]—specifically lung transplant recipients on a regimen of immunosuppressive drugs. The reported skin manifestations consisted of severely pruritic (itchy) velvet-textured plaques initially interpreted clinically as drug side effects. Evidence of actively replicating HPyV7 was identified in affected tissue, supporting the hypothesis that the virus caused the rash.

Additional information

Type and quantity

Direct One-Step PCR (100 reactions), Direct One-Step PCR (200 reactions), Direct One-Step PCR (500 reactions), One-Step PCR (100 reactions), One-Step PCR (200 reactions), One-Step PCR (500 reactions), Standard PCR (100 reactions), Standard PCR (200 reactions), Standard PCR (500 reactions), Oligo (100 reactions)

Copy number positive control

No, Yes