Human Parainfluenza Virus Type 3 (HPIV3)

307.212,550.07

Validated qPCR / RT-PCR kit for Human Parainfluenza Virus Type 3 (HPIV3)

Detection channel: FAM (518nm)

Available in different versions:

-Direct One-Step PCR (extraction-less direct detection)

-One-Step PCR (extraction kit needed)

-Standard PCR (extraction kit and RT step needed)

-Oligo (without PCR mix)

In 100/200/500 reactions, with optional copy number positive control

(Not for use in diagnostic procedures)

Clear
SKU: PCR-00359-K Categories: , , ,

Description

HPIV-1, HPIV-2 and HPIV-3 cause lower respiratory infections. Upper respiratory infections (URI) are also important in the context of HPIV, however, they are caused to a lesser extent by the virus.

The highest rates of serious HPIV illnesses occur among young children, and surveys have shown that about 75% of children aged 5 or older have antibodies to HPIV-1.

Repeated infection throughout the life of the host is not uncommon and symptoms of later breakouts include upper respiratory tract illness, such as cold and a sore throat.

HPIV-3 has been closely associated with bronchiolitis and pneumonia and principally targets those aged <1 year.

Important epidemiological factors that are associated with a higher risk of infection and mortality are those who are immuno-compromised and may be taken ill with more extreme forms of LRI.[13] Associations between HPIVs and neurologic disease are known; for example, hospitalisation with certain HPIVs has a strong association with febrile seizures. HPIV-4B has the strongest association (up to 62%) followed by hPIV-3 and -1.

HPIVs have also been linked with rare cases of virally caused meningitis and Guillain–Barré syndrome.

Additional information

Type and quantity

Direct One-Step PCR (100 reactions), Direct One-Step PCR (200 reactions), Direct One-Step PCR (500 reactions), One-Step PCR (100 reactions), One-Step PCR (200 reactions), One-Step PCR (500 reactions), Standard PCR (100 reactions), Standard PCR (200 reactions), Standard PCR (500 reactions), Oligo (100 reactions)

Copy number positive control

No, Yes