Epstein-Barr Virus (EBV)

307.212,550.07

Validated qPCR / RT-PCR kit for Epstein-Barr Virus (EBV)

Detection channel: FAM (518nm)

Available in different versions:

-Direct One-Step PCR (extraction-less direct detection)

-One-Step PCR (extraction kit needed)

-Standard PCR (extraction kit and RT step needed)

-Oligo (without PCR mix)

In 100/200/500 reactions, with optional copy number positive control

(Not for use in diagnostic procedures)

Clear

Description

The Epstein–Barr virus (EBV), formally called Human gammaherpesvirus 4, is one of the nine known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.

It is best known as the cause of infectious mononucleosis (“mono” or “glandular fever”). It is also associated with various non-malignant, premalignant, and malignant Epstein–Barr virus-associated lymphoproliferative diseases such as Burkitt lymphoma, hemophagocytic lymphohistiocytosis, and Hodgkin’s lymphoma; non-lymphoid malignancies such as gastric cancer and nasopharyngeal carcinoma; and conditions associated with human immunodeficiency virus such as hairy leukoplakia and central nervous system lymphomas. The virus is also associated with the childhood disorders of Alice in Wonderland syndrome and acute cerebellar ataxia and, based on some evidence, higher risks of developing certain autoimmune diseases, especially dermatomyositis, systemic lupus erythematosus, rheumatoid arthritis, Sjögren’s syndrome, and multiple sclerosis.

Infection with EBV occurs by the oral transfer of saliva and genital secretions. Most people become infected with EBV and gain adaptive immunity, with about 90% of adults having evidence of previous infection.

Additional information

Type and quantity

Direct One-Step PCR (100 reactions), Direct One-Step PCR (200 reactions), Direct One-Step PCR (500 reactions), One-Step PCR (100 reactions), One-Step PCR (200 reactions), One-Step PCR (500 reactions), Standard PCR (100 reactions), Standard PCR (200 reactions), Standard PCR (500 reactions), Oligo (100 reactions)

Copy number positive control

No, Yes