Encephalitozoon intestinalis is a parasite. It can cause microsporidiosis.
Encephalitozoon cuniculi is a mammalian microsporidial pathogen with world-wide distribution. An important cause of neurologic and renal disease in rabbits, E. cuniculi can also cause disease in immunocompromised people.
E. hellem manifestations include keratoconjunctivitis, infection of respiratory and genitourinary tract, and disseminated infection. It has been identified in immunocompromised people.