Dobrava-Belgrade virus (DOBV)

307.212,550.07

Validated qPCR / RT-PCR kit for Dobrava-Belgrade virus (DOBV)

Detection channel: FAM (518nm)

Available in different versions:

-Direct One-Step PCR (extraction-less direct detection)

-One-Step PCR (extraction kit needed)

-Standard PCR (extraction kit and RT step needed)

-Oligo (without PCR mix)

In 100/200/500 reactions, with optional copy number positive control

(Not for use in diagnostic procedures)

Clear
SKU: PCR-00254-K Categories: , , , , ,

Description

Dobrava-Belgrade virus (DOBV), also known as Dobrava virus is a hantavirus with high fatality rates. It is one of several species of Hantavirus that is the causative agent of severe Hantavirus hemorrhagic fever with renal syndrome.

It was first isolated in Slovenia and subsequently found in striped field mice in Russia and other parts of Eastern Europe. It has also been found in Germany but the reservoir host there is unknown. Transmission by aerosolized rodent excreta still remains the only known way the virus is transmitted to humans.

Variant DOBV genotypes have different degrees of pathogenicity. Initial symptoms begin suddenly and include intense headaches, back and abdominal pain, fever, chills, nausea, and blurred vision. Individuals may have flushing of the face, inflammation or redness of the eyes, or a rash. Later symptoms can include low blood pressure, acute shock, vascular leakage, and acute kidney failure, which can cause severe fluid overload.

 

Additional information

Type and quantity

Direct One-Step PCR (100 reactions), Direct One-Step PCR (200 reactions), Direct One-Step PCR (500 reactions), One-Step PCR (100 reactions), One-Step PCR (200 reactions), One-Step PCR (500 reactions), Standard PCR (100 reactions), Standard PCR (200 reactions), Standard PCR (500 reactions), Oligo (100 reactions)

Copy number positive control

No, Yes