Candida tropicalis is a species of yeast in the genus Candida. It is a common pathogen in neutropenic hosts, in whom it may spread through the bloodstream to peripheral organs.
Candida species are very pervasive yeasts that are distributed worldwide geographically. They are more likely to be found in tropical climate where temperature and humidity will enhance the adaptability of C. tropicalis. C. tropicalis is considered as an osmotolerant yeast; microorganisms that are able to survive in high salt concentration and able to develop fungal persistence in saline environments.
n tropical countries, C. tropicalis is one of the most common colonizer and pathogen causing human disease, especially found on human skin, in the gastrointestinal tract and also in female genitourinary tract. It can be transmitted between health-care workers and patients, especially in environments such as hospitals.
C. tropicalis is the second most virulent Candida species that can significantly affect by spreading through the weakened immune system host. C. tropicalis is virulent due to its ability to produce biofilm, secrete lytic enzymes, adhere to epithelial and endothelial cells, and undergo transition of bud to hyphae.